- 25-azido-1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosane
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2026-07-24
- CAS:1818294-30-2
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Trityl-PEG7-Azide Basic information |
| | Trityl-PEG7-Azide Chemical Properties |
| solubility | Soluble in DMSO, DCM, DMF |
| | Trityl-PEG7-Azide Usage And Synthesis |
| Description | Trityl-PEG8-azide trityl protected click chemistry PEG linker containing an azide group and a trityl protected group. The azide group enables Click Chemistry. Trityl group can be removed under acid conditions or hydrogenolysis. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | Trityl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Trityl-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Trityl-PEG7-Azide Preparation Products And Raw materials |
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