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| | 6-Acryloyl-2-dimethylaminonaphthalene Basic information |
| Product Name: | 6-Acryloyl-2-dimethylaminonaphthalene | | Synonyms: | ACRYLODAN;ACRYLODAN [6-ACRYLOYL-2-DIMETHYLAMINONAPHTHALENE];1-(6-(Dimethylamino)-2-naphthalenyl)-2-propen-1-one;2-Propen-1-one, 1-(6-(dimethylamino)-2-naphthalenyl)-;1-(6-(Dimethylamino)naphthalen-2-yl)prop-2-en-1-one;1-(6-Dimethylamino-naphthalen-2-yl)-propenone;Acrylodan [6-Acryloyl-2-dimethylaminophthalene];Acrylodan [6-acryloyl-2-dimethylaminonaphthalene] - 5 mg | | CAS: | 86636-92-2 | | MF: | C15H15NO | | MW: | 225.29 | | EINECS: | | | Product Categories: | | | Mol File: | 86636-92-2.mol |  |
| | 6-Acryloyl-2-dimethylaminonaphthalene Chemical Properties |
| Melting point | 130-131 °C(Solv: ethanol (64-17-5); water (7732-18-5)) | | Boiling point | 388.3±24.0 °C(Predicted) | | density | 1.100±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | form | Solid | | pka | 4.32±0.40(Predicted) | | color | Light yellow to yellow |
| | 6-Acryloyl-2-dimethylaminonaphthalene Usage And Synthesis |
| Description | Acrylodan is a sulfhydryl-reactive fluorescent probe for protein structural studies. | | Uses | Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys34[1][2]. | | References | [1] Sarah F Stuart, et al. A two-step mechanism for the folding of actin by the yeast cytosolic chaperonin. J Biol Chem. 2011 Jan 7;286(1):178-84. DOI:10.1074/jbc.M110.166256
[2] K Flora, et al. Unfolding of acrylodan-labeled human serum albumin probed by steady-state and time-resolved fluorescence methods. Biophys J. 1998 Aug;75(2):1084-96. DOI:10.1016/S0006-3495(98)77598-8 |
| | 6-Acryloyl-2-dimethylaminonaphthalene Preparation Products And Raw materials |
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