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Methyl 2-oxindole-4-carboxylate

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Methyl 2-oxindole-4-carboxylate manufacturers

Methyl 2-oxindole-4-carboxylate Basic information
Product Name:Methyl 2-oxindole-4-carboxylate
Synonyms:methyl 2-oxo-2,3-dihydro-1H-indole-4-carboxylate;4-Methoxycarbonyl-2-oxindole;Methyl 2-oxindole-4-carbo...;1H-Indole-4-carboxylic acid, 2,3-dihydro-2-oxo-, Methyl ester;METHYL OXINDOLE-4-CARBOXYLATE;METHYL 2-OXINDOLE-4-CARBOXYLATE;Methyl 2-oxoindoline-4-carboxylate;Methyl-2-Dxoindline-4-carboxylate
CAS:90924-46-2
MF:C10H9NO3
MW:191.18
EINECS:2017-001-1
Product Categories:Indole/indoline/oxindole;Indole and Indoline;Indole;Indoles
Mol File:90924-46-2.mol
Methyl 2-oxindole-4-carboxylate Structure
Methyl 2-oxindole-4-carboxylate Chemical Properties
storage temp. Store at 0-8 °C
Appearanceyellow solid
Safety Information
HS Code 2933998090
MSDS Information
Methyl 2-oxindole-4-carboxylate Usage And Synthesis
Synthesis
Benzeneacetic acid, 2-(methoxycarbonyl)-6-nitro-, methyl ester

93534-73-7

Methyl 2-oxindole-4-carboxylate

90924-46-2

General method: Compound 22 (15.8 mmol) or Compound 23 (15.8 mmol) was dissolved in methanol, 10 μl of 10% Pd-C catalyst was added and hydrogen was passed through. The reaction mixture was stirred for 5 hours. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated. The residue obtained was purified by recrystallization from methanol to give methyl 4-carboxylate dihydroindol-2-one.

References[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 20, p. 4557 - 4561
Methyl 2-oxindole-4-carboxylate Preparation Products And Raw materials
Raw materialsBenzeneacetic acid, 2-(methoxycarbonyl)-6-nitro-, methyl ester-->Palladium-->Hydrogen-->Activated carbon-->Methanol
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