- Ruscogenin
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2026-05-15
- CAS:472-11-7
- Min. Order:
- Purity: 0.99
- Supply Ability:
- RUSCOGENIN
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- $1.00 / 1KG
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2025-12-12
- CAS:472-11-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 2000KG
- Ruscogenin
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- $0.00 / 20mg
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2023-02-24
- CAS:472-11-7
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | RUSCOGENIN Basic information |
| | RUSCOGENIN Chemical Properties |
| Melting point | 198-202℃ | | Boiling point | 563.1±50.0 °C(Predicted) | | density | 1.18 | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | | pka | 14.56±0.70(Predicted) | | form | Solid | | color | White | | Major Application | metabolomics
vitamins, nutraceuticals, and natural products | | Cosmetics Ingredients Functions | SKIN CONDITIONING | | InChIKey | QMQIQBOGXYYATH-ORLFXEBYNA-N | | SMILES | C[C@H](CC1)CO[C@]21O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)C[C@@H](O)[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@@]3([H])[C@@H]2C |
| Safety Statements | 24/25 | | WGK Germany | WGK 3 | | HS Code | 29389090 | | Storage Class | 11 - Combustible Solids |
| | RUSCOGENIN Usage And Synthesis |
| Chemical Properties | White powder | | Uses | A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner. | | Definition | ChEBI: Ruscogenin is a triterpenoid. | | Biological Activity | Ruscogenin is a well-known compound for down-regulating nuclear factor kappa B (NF-KB), intercellular adhesion molecule-1 (ICAM-1), tissue factor (TF), inducible NO synthase (iNOS), and modulating inflammatory pathways. It displays anti-inflammatory properties by inhibiting lipopolysaccharide (LPS)-induced acute lung injury (ALI), and improving diabetic nephropathy in in vivo studies. Ruscogenin also exerts neuroprotective properties and protects the brain against ischemic injury in mouse model. It elicits anti-tumor properties by inducing ferroptosis in pancreatic cancer cells in both in vitro and in vivo studies. | | target | PGE | TNF-α | NF-kB | p65 | NO | NOS | COX | ERK | JNK | Akt | p38MAPK | PKA | cAMP | IL Receptor |
| | RUSCOGENIN Preparation Products And Raw materials |
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