AZD2906

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Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
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Company Name: BOC Sciences  
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Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
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AZD2906 manufacturers

  • AZD2906
  • AZD2906 pictures
  • $427.00
  • 2026-04-22
  • CAS:1034148-15-6
  • Purity:
  • Supply Ability: 10g
  • AZD2906
  • AZD2906 pictures
  • $427.00
  • 2025-08-22
  • CAS:1034148-15-6
  • Purity:
  • Supply Ability: 10g
AZD2906 Basic information
Product Name:AZD2906
Synonyms:AZD2906;Cyclopropanecarboxamide, N-[(1R,2S)-2-[[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy]-2-(6-methoxy-3-pyridinyl)-1-methylethyl]-, rel-;AZD2906,AZD-2906
CAS:1034148-15-6
MF:C26H25FN4O3
MW:460.5
EINECS:
Product Categories:
Mol File:1034148-15-6.mol
AZD2906 Structure
AZD2906 Chemical Properties
Boiling point 651.4±55.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 125 mg/mL (271.44 mM)
form Solid
pka15.03±0.20(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
AZD2906 Usage And Synthesis
UsesAZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats. AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1].
in vivo

AZD2906 (5, 25, 50 mg/kg, p.o.) increases micronucleated immature erythrocytes (MIE) in the bone marrow of rats after treatment for 2 days[1].
AZD2906 (5, 25 mg/kg, p.o.) induces an accumulation of glycogen in the liver of rats, and exhibits cortical lymphocytic atrophy of a moderate to marked degree in the thymus of rats[1].

Animal Model:Male Wistar Han rats (10 weeks old)[1]
Dosage:5, 25, 50 mg/kg
Administration:P.O. for 2 days
Result:Caused significant increase in micronucleated immature erythrocytes (MIE) at all doses after analysis of the standard 2000 IE.
References[1] Hayes JE, et al. Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. I: glucocorticoid receptor agonism. Mutagenesis. 2013 Mar;28(2):227-32. DOI:10.1093/mutage/ges076
AZD2906 Preparation Products And Raw materials
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