Product Details
| Product Name:
AZD2906 |
CAS No.:
1034148-15-6 |
| Supply Ability:
10g |
Release date:
2025/08/22 |
Product Introduction
Bioactivity
| Name | AZD2906 |
| Description | AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow. |
| In vitro | AZD2906 is a selective glucocorticoid receptor (GR) with IC50 values of 2.2 nM and 0.3 nM in human and rat PBMC, and 41.6 nM and 7.5 nM in human and rat whole blood, respectively[1]. |
| In vivo | AZD2906 (5, 25, 50 mg/kg, p.o.) increases micronucleated immature erythrocytes (MIE) in the bone marrow of rats after 2 days of treatment and induces glycogen accumulation in the liver at 5 and 25 mg/kg, p.o., while causing moderate to marked cortical lymphocytic atrophy in the thymus of rats[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (271.44 mM), Sonication is recommended.
|
| Keywords | Glucocorticoid receptor, Rat whole blood | Glucocorticoid receptor, Rat PBMC | Glucocorticoid receptor, Human whole blood | Glucocorticoid receptor, Human PBMC | AZD-2906 | AZD2906 | AZD 2906 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Recommended supplier
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Price |
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Suppliers |
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$427.00/5mg |
VIP4Y
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TargetMol Chemicals Inc.
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2024-10-28 |
United States