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Ethylhydrocupreine manufacturers
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| | Ethylhydrocupreine Basic information |
| Product Name: | Ethylhydrocupreine | | Synonyms: | optochin;optoquine;ethylhydrocupreine free base*crystalline;Numoquine;Optochine;Hydrocupureine ethyl ether;Cinchonan-9-ol,6'-ethoxy-10,11-dihydro-, (8a,9R)-;6’-ethoxy-10,11-dihydro-,(8-alpha,9r)-cinchonan-9-o | | CAS: | 522-60-1 | | MF: | C21H28N2O2 | | MW: | 340.46 | | EINECS: | 208-333-5 | | Product Categories: | Miscellaneous | | Mol File: | 522-60-1.mol |  |
| | Ethylhydrocupreine Chemical Properties |
| Melting point | 123-128° when solvent-free | | alpha | D25 -136.2° (alcohol) | | Boiling point | 476.25°C (rough estimate) | | density | 1.1027 (rough estimate) | | refractive index | 1.6180 (estimate) | | storage temp. | 2-8°C |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | RTECS | MW5950000 |
| | Ethylhydrocupreine Usage And Synthesis |
| Uses | Ethylhydrocupreine is an antibiotic tested against isolates of Streptococcus mitis resulting in an 100% resistance. Also, ethylhydrocupreine susceptibility test is a key method for differentiating Streptococcus pneumoniae from other α-hemolytic streptococci. | | Definition | ChEBI: A cinchona alkaloid consisting of 10,11-dihydrocinchonan bearing hydroxy and ethoxy substituents at positions 9 and 6' respectively. | | in vivo | The injection of 1 cc. of a 24 hour dextrose blood broth culture of virulent Type I pneumococci into the right pleural cavity of guinea pigs produces acute suppurative pleuritis on both sides associated with suppurative pericarditis. The injection of 1 cc. of 1:500 solutions of Ethylhydrocupreine hydrochloride into each pleural cavity of guinea pigs at varying intervals up to 24 hours after pleural infection has usually shown a marked curative influence. Similar results are observed with dogs[1]. |
| | Ethylhydrocupreine Preparation Products And Raw materials |
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