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Ethylhydrocupreine hydrochloride

Ethylhydrocupreine hydrochloride Suppliers list
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Ethylhydrocupreine hydrochloride manufacturers

Ethylhydrocupreine hydrochloride Basic information
Product Name:Ethylhydrocupreine hydrochloride
Synonyms:OPTICHIN HYDROCHLORIDE;hydrocupreine,ethylester,hydrochloride;Ethylhydrocupreine HCl,Optochin HCl;neumolisina;numoquinhydrochloride;o-ethyl-hydrocupreinhydrochloride;optochinhydrochloride;optoquinhydrochloride
CAS:3413-58-9
MF:C21H29ClN2O2
MW:376.92
EINECS:222-302-3
Product Categories:Miscellaneous
Mol File:3413-58-9.mol
Ethylhydrocupreine hydrochloride Structure
Ethylhydrocupreine hydrochloride Chemical Properties
Melting point 121-123°C
alpha D21 -123.6° (water)
storage temp. 2-8°C
solubility DMSO : 125 mg/mL (331.64 mM; Need ultrasonic)
form Solid
color White to off-white
Sensitive Light Sensitive
BRN 4055970
Major Applicationforensics and toxicology
pharmaceutical (small molecule)
veterinary
InChIKeyQNRATNLHPGXHMA-XZHTYLCXSA-N
SMILESCl[H].[H][C@@]12CCN(C[C@@H]1CC)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OCC)cc34
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
RTECS MW6300000
8
HS Code 29392900
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Ethylhydrocupreine hydrochloride Usage And Synthesis
UsesEthylhydrocupreine Hydrochloride is a reagent used in the alteration in bacterial morphology. Also, it inhibits methylene blue (MB) reductase activity; Anti-pneumococcal analog of quinine-HC1 which stimulated the diaphorase activity of pig heart muscle and Escherichia coli lipoyl dehydrogenase.
in vivo

The injection of 1 cc. of a 24 hour dextrose blood broth culture of virulent Type I pneumococci into the right pleural cavity of guinea pigs produces acute suppurative pleuritis on both sides associated with suppurative pericarditis. The injection of 1 cc. of 1:500 solutions of Ethylhydrocupreine hydrochloride into each pleural cavity of guinea pigs at varying intervals up to 24 hours after pleural infection has usually shown a marked curative influence. Similar results are observed with dogs[1].

IC 50Plasmodium
Purification MethodsRecrystallise it from H2O [UV: Heidt & Forbes J Am Chem Soc 55 2701 1933]. [Beilstein 24 H 385, 24 III/IV 1446.]
Ethylhydrocupreine hydrochloride Preparation Products And Raw materials
Tag:Ethylhydrocupreine hydrochloride(3413-58-9) Related Product Information
Cupric acetate monohydrate Quinine Copper Ethylhydrocupreine Ethylhydrocupreine hydrochloride (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine 4-Heptylpyridine Quinuclidine hydrochloride 4-(2-Aminoethyl)pyridine HCl Hydroquinine