ETHYLHYDROCUPREINE HYDROCHLORIDE manufacturers
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| | ETHYLHYDROCUPREINE HYDROCHLORIDE Basic information |
| Product Name: | ETHYLHYDROCUPREINE HYDROCHLORIDE | | Synonyms: | OPTICHIN HYDROCHLORIDE;ETHYLHYDROCUPREINE HYDROCHLORIDE;hydrocupreine,ethylester,hydrochloride;Ethylhydrocupreine HCl,Optochin HCl;neumolisina;numoquinhydrochloride;o-ethyl-hydrocupreinhydrochloride;optochinhydrochloride | | CAS: | 3413-58-9 | | MF: | C21H29ClN2O2 | | MW: | 376.92 | | EINECS: | 222-302-3 | | Product Categories: | Miscellaneous | | Mol File: | 3413-58-9.mol |  |
| | ETHYLHYDROCUPREINE HYDROCHLORIDE Chemical Properties |
| Melting point | 121-123°C | | alpha | D21 -123.6° (water) | | storage temp. | 2-8°C | | solubility | DMSO : 125 mg/mL (331.64 mM; Need ultrasonic) | | form | Solid | | color | White to off-white | | Sensitive | Light Sensitive | | BRN | 4055970 | | Major Application | forensics and toxicology
pharmaceutical (small molecule)
veterinary | | InChIKey | QNRATNLHPGXHMA-XZHTYLCXSA-N | | SMILES | Cl[H].[H][C@@]12CCN(C[C@@H]1CC)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OCC)cc34 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-36-26 | | WGK Germany | 3 | | RTECS | MW6300000 | | F | 8 | | HS Code | 29392900 | | Storage Class | 11 - Combustible Solids |
| | ETHYLHYDROCUPREINE HYDROCHLORIDE Usage And Synthesis |
| Uses | Ethylhydrocupreine Hydrochloride is a reagent used in the alteration in bacterial morphology. Also, it inhibits methylene blue (MB) reductase activity; Anti-pneumococcal analog of quinine-HC1 which stimulated the diaphorase activity of pig heart muscle and Escherichia coli lipoyl dehydrogenase. | | in vivo | The injection of 1 cc. of a 24 hour dextrose blood broth culture of virulent Type I pneumococci into the right pleural cavity of guinea pigs produces acute suppurative pleuritis on both sides associated with suppurative pericarditis. The injection of 1 cc. of 1:500 solutions of Ethylhydrocupreine hydrochloride into each pleural cavity of guinea pigs at varying intervals up to 24 hours after pleural infection has usually shown a marked curative influence. Similar results are observed with dogs[1]. | | IC 50 | Plasmodium | | Purification Methods | Recrystallise it from H2O [UV: Heidt & Forbes J Am Chem Soc 55 2701 1933]. [Beilstein 24 H 385, 24 III/IV 1446.] |
| | ETHYLHYDROCUPREINE HYDROCHLORIDE Preparation Products And Raw materials |
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