ZEN-3411 manufacturers
- ZEN-3411
-
- $210.00
-
2026-07-14
- CAS:1952264-36-6
- Purity: 98.84%
- Supply Ability: 10g
- ZEN-3411
-
- $210.00
-
2026-07-14
- CAS:1952264-36-6
- Purity: 98.84%
- Supply Ability: 10g
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| | ZEN-3411 Basic information |
| Product Name: | ZEN-3411 | | Synonyms: | ZEN-3411;1H-Benzimidazol-4-amine, 6-(3,5-dimethyl-4-isoxazolyl)-1-[[4-(2-oxiranyl)phenyl]methyl]-;ZEN3411,ZEN 3411 | | CAS: | 1952264-36-6 | | MF: | C21H20N4O2 | | MW: | 360.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1952264-36-6.mol |  |
| | ZEN-3411 Chemical Properties |
| | ZEN-3411 Usage And Synthesis |
| Description | ZEN-3411 is a BET inhibitor for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4. | | Uses | ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1]. | | IC 50 | BRD4 (BD1): 0.05 μM (IC50); BRD4 (BD2): 0.05 μM (IC50); BRD4(BD1BD2): 0.06 μM (IC50) | | References | [1] Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211. DOI:10.1021/acs.jmedchem.8b00666 |
| | ZEN-3411 Preparation Products And Raw materials |
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