Company Name: |
Beijing Biocreative Technology Co., Ltd.
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Tel: |
15522676233 |
Email: |
3007606172@qq.com |
Products Intro: |
Product Name:ZEN-3411 CAS:1952264-36-6 Purity:99% HPLC Package:1.0mg; 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 2.0g;
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ZEN-3411 manufacturers
- ZEN-3411
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- $350.00 / 1mg
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2025-07-18
- CAS:1952264-36-6
- Min. Order:
- Purity: 98.84%
- Supply Ability: 10g
- ZEN-3411
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- $350.00 / 1mg
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2025-05-19
- CAS:1952264-36-6
- Min. Order:
- Purity: 97.77%
- Supply Ability: 10g
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| ZEN-3411 Basic information |
Product Name: | ZEN-3411 | Synonyms: | ZEN-3411;1H-Benzimidazol-4-amine, 6-(3,5-dimethyl-4-isoxazolyl)-1-[[4-(2-oxiranyl)phenyl]methyl]-;ZEN3411,ZEN 3411 | CAS: | 1952264-36-6 | MF: | C21H20N4O2 | MW: | 360.41 | EINECS: | | Product Categories: | | Mol File: | 1952264-36-6.mol |  |
| ZEN-3411 Chemical Properties |
| ZEN-3411 Usage And Synthesis |
Description | ZEN-3411 is a BET inhibitor for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4. | Uses | ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1]. | IC 50 | BRD4 (BD1): 0.05 μM (IC50); BRD4 (BD2): 0.05 μM (IC50); BRD4(BD1BD2): 0.06 μM (IC50) | References | [1] Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211. DOI:10.1021/acs.jmedchem.8b00666 |
| ZEN-3411 Preparation Products And Raw materials |
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