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N-(2-Furoyl)glycine

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Company Name: Energy Chemical  
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N-(2-Furoyl)glycine manufacturers

N-(2-Furoyl)glycine Basic information
Product Name:N-(2-Furoyl)glycine
Synonyms:n-2-furoyl-glycin;2-(2-furylcarbonylamino)acetic acid;Pyromucuric acid;N-(2-furoyl)glycinate;2-(furan-2-carbonylamino)acetic acid;AKOS BBS-00000709;furfuroylglycine;furoilglicina
CAS:5657-19-2
MF:C7H7NO4
MW:169.13
EINECS:
Product Categories:Glycine Derivatives;Peptide Synthesis;Unnatural Amino Acid Derivatives
Mol File:5657-19-2.mol
N-(2-Furoyl)glycine Structure
N-(2-Furoyl)glycine Chemical Properties
Melting point 163-165 °C(lit.)
Boiling point 466.0±25.0 °C(Predicted)
density 1.367±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka3.66±0.10(Predicted)
color White to Off-White
biological sourcesynthetic
Water Solubility >21.55 mg/mL in Water with ultrasonic;
Stability:Hygroscopic
Major Applicationpeptide synthesis
InChI1S/C7H7NO4/c9-6(10)4-8-7(11)5-2-1-3-12-5/h1-3H,4H2,(H,8,11)(H,9,10)
InChIKeyKSPQDMRTZZYQLM-UHFFFAOYSA-N
SMILESOC(=O)CNC(=O)c1ccco1
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 2
RTECS MC0555300
HazardClass IRRITANT
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
SigmaAldrich English
N-(2-Furoyl)glycine Usage And Synthesis
Uses2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.
DefinitionChEBI: N-(2-furoyl)glycine is a glycine derivative that is the carboxamide obtained by the formal condensation of the amino group of glycine with 2-furoic acid. It has a role as a human metabolite. It is a N-acylglycine and a member of furans. It is functionally related to a 2-furoic acid. It is a conjugate acid of a N-(2-furoyl)glycinate.
IC 50Human Endogenous Metabolite; Microbial Metabolite
N-(2-Furoyl)glycine Preparation Products And Raw materials
Tag:N-(2-Furoyl)glycine(5657-19-2) Related Product Information
FURALAXYL 2-[(Furan-2-carbonyl)-amino]-3-methyl-butyric acid 1-(2-Furylcarbonyl)-4-hydroxy-2-pyrrolidinecarboxylic acid 2-[(Furan-2-carbonyl)-amino]-3-(4-hydroxy-phenyl)-propionic acid N-(2-Furoyl)alanine N-(2-Furoyl)glycine methyl ester N-(2-Furoyl)glycine 2-[(Furan-2-carbonyl)-amino]-3-phenyl-propionic acid 2-(Furan-2-carbonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [(5-Bromo-furan-2-carbonyl)-amino]-acetic acid 2-(2-Furoylamino)-4-(methylthio)butanoic acid 4-amino-2-(2-furoylamino)-4-oxobutanoic acid AURORA 673 AURORA 2283 4-carbamoyl-2-(furan-2-ylformamido)butanoic acid 1-[(5-methylfuran-2-yl)carbonyl]pyrrolidine-2-carboxylic acid AKOS BBS-00007559 1-(Furan-2-carbonyl)-4-hydroxy-pyrrolidine-2-carboxylic acid methyl ester