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| | Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 Basic information |
| Product Name: | Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 | | Synonyms: | MMP-3 INHIBITOR I;MMP PEPTIDE INHIBITOR I;STROMELYSIN-1 INHIBITOR;AC-RCGVPD-NH2;Acetyl-StroMelysin-1 Activation Peptide (74-79) aMide (huMan, horse, Mouse), Acetyl-MMP-3 Precursor (91-96) aMide (huMan, horse, Mouse);Reaxys ID: 15522609;Matrix Metalloproteinase-3 Inhibitor;MMP-3 INHIBITOR;MATRIX METALLOPROTEINASE-3 INHIBITOR | | CAS: | 158841-76-0 | | MF: | C27H46N10O9S | | MW: | 686.78 | | EINECS: | | | Product Categories: | peptide | | Mol File: | 158841-76-0.mol |  |
| | Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 Chemical Properties |
| density | 1.531±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | White to off-white solid. | | pka | 4.097±0.10(predicted) | | color | white | | Water Solubility | water: 1mg/mL | | Sequence | Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 Usage And Synthesis |
| Uses | MMP3 inhibitor 3 is an inhibitor of MMP3. MMP3 inhibitor 3 can used to study breast cancer[1]. | | Biological Activity | Cell permeable: no', 'Primary Target
MMP-3', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 5 μM against MMP-3 | | References | [1] Holliday DL, et al. Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion. Breast Cancer Res. 2007;9(5):R67. DOI:10.1186/bcr1775 |
| | Ac-Arg-Cys-Gly-Val-Pro-Asp-NH2 Preparation Products And Raw materials |
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