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jinansmile Gold |
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13583121644 |
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Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate manufacturers
- Dihydropyridine
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- $8.70
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2026-05-28
- CAS:1149-23-1
- Min. Order: 10kg
- Purity: 99%
- Supply Ability: 10000kg
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| | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Basic information |
| Product Name: | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | | Synonyms: | DIETHYL 2,6-DIMETHYL-1,4-DIHYDROPYRIDINEDICARBOXYLATE;DIETHYL 1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE;AURORA 4780;3,5-DICARBETHOXY-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE;3,5-BIS(CARBOETHOXY)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE;1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER;RARECHEM AQ NN 0171;5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-diethylester | | CAS: | 1149-23-1 | | MF: | C13H19NO4 | | MW: | 253.29 | | EINECS: | 214-561-6 | | Product Categories: | Pyridines, Pyrimidines, Purines and Pteredines;Pharmaceutical Intermediates;C9 to C46;Heterocyclic Building Blocks;Heterocycle-Pyridine series;Building Blocks;C13 to C15;Chemical Synthesis;1149-23-1;VX:15169101773;fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis, pharmaceutical intermediates;Pyridines;Heterocyclic Building Blocks;C9 to C46 | | Mol File: | 1149-23-1.mol |  |
| | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Chemical Properties |
| Melting point | 178-183 °C(lit.) | | Boiling point | 351.8±42.0 °C(Predicted) | | density | 1.104±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Soluble in organic solvents. | | pka | 3.50±0.70(Predicted) | | form | Solid | | color | Yellow | | λmax | 374nm(EtOH)(lit.) | | InChI | InChI=1S/C13H19NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h14H,5-7H2,1-4H3 | | InChIKey | LJXTYJXBORAIHX-UHFFFAOYSA-N | | SMILES | C1(C)NC(C)=C(C(OCC)=O)CC=1C(OCC)=O | | CAS DataBase Reference | 1149-23-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 2 | | RTECS | US7970100 | | HS Code | 29333990 | | Toxicity | LD50 oral in dog: > 12gm/kg |
| | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Usage And Synthesis |
| Chemical Properties | Light green solid | | Uses | 3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine is a dihydropyridine derivative that have been tested for antimicrobial activities. | | Uses | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is a hydrogen source in conjugate reduction and organocatalytic reductive amination. It is used as a hydrogen source in organocatalytic reductive amination and conjugate reduction. | | Application | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DTP) was used to study the mechanism of electrochemical oxidation of DTP in ethanol/water solutions on a glassy carbon electrode. | | Hazard | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] | | Toxicology | rat LD50 intraperitoneal >16 gm/kg
mouse LD50 oral >32 gm/kg
mouse LD50 intraperitoneal >30 gm/kg
dog LD50 oral >12 gm/kg | | Synthesis | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is prepared by the reaction of formaldehyd and ethyl acetoacetate in the presence of an inert gas.
 | | Synthesis | Hantzsch Dihydropyridine (Pyridine) Synthesis reaction allows the preparation of dihydropyridine derivatives by
condensation of an aldehyde with two equivalents of a β-ketoester in the
presence of ammonia. Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate can be produced by using this method.
 | | Purification Methods | recrystallization from EtOH or flash chromatography with petroleum/ethyl acetate (7:3) |
| | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Preparation Products And Raw materials |
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