Cyclic di-UMP sodium salt

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Cyclic di-UMP sodium salt Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: ChemeGen  
Tel: 18818260767
Email: 2625930290@qq.com

Cyclic di-UMP sodium salt manufacturers
Cyclic di-UMP sodium salt Basic information
Product Name:Cyclic di-UMP sodium salt
Synonyms:Cyclic di-UMP sodium salt
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
Cyclic di-UMP sodium salt Structure
Cyclic di-UMP sodium salt Chemical Properties
solubility Water: soluble
Safety Information
MSDS Information
Cyclic di-UMP sodium salt Usage And Synthesis
DescriptionCyclic di-UMP is a pyrimidine-containing cyclic dinucleotide (CDN).1 It is produced by bacterial cGAS/DncV-like nucleotidyltransferases (CD-NTases), such as LpCdnE02 from L. pneumophila, and binds to cGAS, in the apo or dsDNA-bound forms, with reduced affinity compared to 2’3’-cGAMP (Item No. 19887) or 3’3’-cGAMP (Item No. 17966).1,2 Cyclic di-UMP is intended for use as a negative control for cyclic di-GMP signaling.WARNING This product is not for human or veterinary use.
References[1] AARON T. WHITELEY. Bacterial cGAS-like enzymes synthesize diverse nucleotide signals[J]. Nature, 2019, 567 7747: 194-199. DOI: 10.1038/s41586-019-0953-5
[2] JUSTIN HALL. The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.[J]. Protein Science, 2017, 26 12: 2367-2380. DOI: 10.1002/pro.3304
Cyclic di-UMP sodium salt Preparation Products And Raw materials
Tag:Cyclic di-UMP sodium salt Related Product Information
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