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- Adibendan
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- $70.00
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2026-09-10
- CAS:100510-33-6
- Purity: 99.81%
- Supply Ability: 10g
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| | Adibendan Basic information |
| Product Name: | Adibendan | | Synonyms: | Adibendan;5,7-Dihydro-7,7-dimethyl-2-(pyridin-4-yl)pyrrolo[2,3-f]benzimidazol-6(1H)-one;BM-14478;Pyrrolo[2,3-f]benzimidazol-6(3H)-one, 5,7-dihydro-7,7-dimethyl-2-(4-pyridinyl)-;Adibendan, 10 mM in DMSO;7,7-Dimethyl-2-(pyridin-4-yl)-3H,5H,6H,7H-imidazo[4,5-F]indol-6-one | | CAS: | 100510-33-6 | | MF: | C16H14N4O | | MW: | 278.314 | | EINECS: | | | Product Categories: | | | Mol File: | 100510-33-6.mol |  |
| | Adibendan Chemical Properties |
| Melting point | 285-288 °C(Solv: methanol (67-56-1)) | | density | 1.302±0.06 g/cm3(Predicted) | | pka | 9.72±0.40(Predicted) |
| | Adibendan Usage And Synthesis |
| Uses | Adibendan (BM 14478), a benzimidazole derivative, is an orally active, selective phosphodiesterase III (PDE III) activity inhibitor (IC50=2.0 μM). Adibendan has IC50 values more than 60-fold higher for the inhibition of PDE I or II. Adibendan is a new cardiotonic agent[1]. | | References | [1] T Bethke, et al. Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts. Naunyn Schmiedebergs Arch Pharmacol. 1988 May;337(5):576-82. DOI:10.1007/BF00182735 |
| | Adibendan Preparation Products And Raw materials |
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