| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Tebufelone
CAS:112018-00-5
Purity:99.00% Package:1mg;5mg;10mg
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| | Tebufelone Basic information |
| Product Name: | Tebufelone | | Synonyms: | Tebufelone;1-(3,5-Ditert-butyl-4-hydroxyphenyl)-5-hexyn-1-one;NE-11740;5-Hexyn-1-one, 1-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-;Tebufelone, 10 mM in DMSO | | CAS: | 112018-00-5 | | MF: | C20H28O2 | | MW: | 300.44 | | EINECS: | | | Product Categories: | | | Mol File: | 112018-00-5.mol |  |
| | Tebufelone Chemical Properties |
| form | Solid | | color | White to off-white |
| | Tebufelone Usage And Synthesis |
| Uses | Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties[1][2]. | | IC 50 | COX-2; 5-LO | | References | [1] S M Weisman, et al. Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism. Agents Actions. 1994 May;41(3-4):156-63. DOI:10.1007/BF02001910
[2] Sebastian Braun, et al. Carborane-Based Tebufelone Analogs and Their Biological Evaluation In Vitro. ChemMedChem. 2023 Jul 17;18(14):e202300206. DOI:10.1002/cmdc.202300206 |
| | Tebufelone Preparation Products And Raw materials |
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