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| | tert-Butylmagnesium chloride Basic information |
| Product Name: | tert-Butylmagnesium chloride | | Synonyms: | tert-Butylmagnesium chloride, 1M in MeTHF;tert-Butylmagnesium chloride [1.0 M solution in THF];tert-Butylmagnesium chloride, 1,7M solution in diethyl ether, AcroSeal§3;tert-Butylmagnesium chloride, 1.7M solution in THF, AcroSeal;tert-Butylmagnesium chloride, 1.7M solution in diethyl ether, AcroSeal;tert-ButylMagnesiuM chloride ,1.0 M in tetrahydrofuran;(1,1-Dimethylethyl)magnesium chloride;Magnesium, chloro(1,1-dimethylethyl)- | | CAS: | 677-22-5 | | MF: | C4H9ClMg | | MW: | 116.87 | | EINECS: | 211-638-6 | | Product Categories: | Classes of Metal Compounds;Grignard Reagents;Grignard Reagents & Alkyl Metals;Mg (Magnesium) Compounds;Synthetic Organic Chemistry;Typical Metal Compounds;AlkylChemical Synthesis;Grignard Reagents;Organic Bases;Organometallic Reagents;Synthetic Reagents;Grignard Reagent;bc0001 | | Mol File: | 677-22-5.mol |  |
| | tert-Butylmagnesium chloride Chemical Properties |
| Melting point | -108℃ (Tetrahydrofuran) | | density | 0.931 g/mL at 25 °C | | Fp | 34 °F | | storage temp. | 2-8°C | | form | Liquid | | color | Clear brown to dark brown | | Water Solubility | Miscible with alcohol and water. | | Sensitive | Air & Moisture Sensitive | | BRN | 3535403 | | InChI | InChI=1S/C4H9.ClH.Mg/c1-4(2)3;;/h1-3H3;1H;/q;;+1/p-1 | | InChIKey | ZDRJSYVHDMFHSC-UHFFFAOYSA-M | | SMILES | C(C)(C)(C)[Mg]Cl | | CAS DataBase Reference | 677-22-5(CAS DataBase Reference) |
| | tert-Butylmagnesium chloride Usage And Synthesis |
| Chemical Properties | clear faint grey to grey, grey-brown or light | | Uses | tert-Butylmagnesium chloride is a Grignard reagent used in organic synthesis. It is also involved in copper-catalyzed cross-coupling reaction with primary-alkyl halides. | | reaction suitability | reaction type: Grignard Reaction | | Synthesis | Preparation of tert-butyl magnesium chloride: remove the oxide film on the surface of the magnesium bar with sandpaper and cut into fine chips. Weigh 3.6 g (0.15 mol) of magnesium chips, added to a four-necked flask equipped with a nitrogen protection device, stirrer, reflux condenser and constant-pressure dropping funnel (the top of the reflux condenser tube is installed with a CaCl2 drying tube), the reaction flask was passed nitrogen for about 10 min to remove the air in the four-necked flask, and then adjusted the flow rate of nitrogen, and in the reaction system continued to pass a very small amount of nitrogen. 35 mL of refined tetrahydrofuran was added to the four-necked flask, and then 13.9 g (0.15 mol) of tert-butyl chloride was weighed, and about 3.5 g of tert-butyl chloride was added to the four-necked flask first, and the remaining 10.4 g of tert-butyl chloride was mixed with 150 mL of refined tetrahydrofuran and added to the constant-pressure dispensing funnel. Add a small grain of iodine, slightly hot, a small amount of bubbles produced, the color of iodine receded, the reaction triggered to keep the reaction system slightly boiled is appropriate, drop after drop, stirring the reaction for 3 ~ 4 h, until the magnesium debris completely disappeared, a gray solution. |
| | tert-Butylmagnesium chloride Preparation Products And Raw materials |
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