(+/-)-N-3-Benzylnirvanol

Request For Quotation
(+/-)-N-3-Benzylnirvanol Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532 18210857532
Email: jkinfo@jkchemical.com
Company Name: Chemsky（shanghai）International Co.,Ltd.  
Tel: 021-50135380
Email: shchemsky@sina.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774 400-920-5774
Email: sales@glpbio.cn
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Tel: +86-400-002-6226
Email: sales@rrkchem.com

(+/-)-N-3-Benzylnirvanol manufacturers
(+/-)-N-3-Benzylnirvanol Basic information
Product Name:(+/-)-N-3-Benzylnirvanol
Synonyms:(+/-)-N-3-Benzylnirvanol;3-Benzyl-5-ethyl-5-phenyl-hydantoi;5-Ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione;3-Benzyl-5-ethyl-5-phenyl-hydantoin;5-ETHYL-5-PHENYL-3-BENZYL-2,4-IMIDAZOLIDINEDIONE;2,4-Imidazolidinedione, 5-ethyl-5-phenyl-3-(phenylmethyl)-
CAS:93879-40-4
MF:C18H18N2O2
MW:294.35
EINECS:
Product Categories:All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:93879-40-4.mol
(+/-)-N-3-Benzylnirvanol Structure
(+/-)-N-3-Benzylnirvanol Chemical Properties
Melting point 134-136°C
density 1.190±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka8.02±0.70(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
(+/-)-N-3-Benzylnirvanol Usage And Synthesis
Description(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (Kis = 0.25 and 5.3 μM, respectively). (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of cholesterol in mice.
Chemical PropertiesWhite Solid
UsesIt is a potent and selective human CYP2C19 inhibitor
References[1] HISASHI SUZUKI. (+)-N-3-Benzyl-nirvanol and (-)-N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19.[J]. Drug Metabolism and Disposition, 2002, 23 1: 235-239. DOI: 10.1124/dmd.30.3.235
[2] JAMES H. MAGUIRE  Iris H H  Akula R Murthy. Hypolipidemic activity of antiepileptic 5-phenylhydantoins in mice[J]. European journal of pharmacology, 1985, 117 1: Pages 135-138. DOI: 10.1016/0014-2999(85)90483-2
(+/-)-N-3-Benzylnirvanol Preparation Products And Raw materials
Tag:(+/-)-N-3-Benzylnirvanol(93879-40-4) Related Product Information
Mephenytoin Hydantoin ETHOTOIN (+/-)-N-3-Benzylnirvanol (R)-(-)-N-3-Benzylnirvanol (S)-(+)-N-3-Benzylnirvanol