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| | Latanoprost Lactone Diol Basic information |
| Product Name: | Latanoprost Lactone Diol | | Synonyms: | LATANOPROST LACTONE DIOL;(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(3R)-3-HYDROXY-5-PHENYLPENTYL]-2H-CYCLOPENTA[B]FURAN-2-ONE;(3AR,4R,5R,6AS)-5-HYDROXY-4-((3R)-3-HYDROXY-5-PHENYLPENTYL)HEXAHYDROCYCLOPENTA[B]FURAN-2-ONE;LP-diol (LT-DI)(Latanprost);LP-diol;2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-, (3aR,4R,5R,6aS)-;(3AR,4R,5R,6aS)-5-Hydroxy-4-((R)-3-hydroxy-5-phenyl-pentyl)hexahydro-2H-cyclopenta[b]furan-2-one;(3AR,4R,5R,6aS)-5-Hydroxy-4-((R)-3-hydroxy-5-phenyl-pentyl)hexahydro-2H-cyclopenta[b]furan-2-o | | CAS: | 145667-75-0 | | MF: | C18H24O4 | | MW: | 304.38 | | EINECS: | | | Product Categories: | | | Mol File: | 145667-75-0.mol |  |
| | Latanoprost Lactone Diol Chemical Properties |
| Melting point | 69-71 ºC | | Boiling point | 523.0±35.0 °C(Predicted) | | density | 1.202 | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 14.58±0.40(Predicted) | | color | White to Off-White | | InChI | InChI=1S/C18H24O4/c19-13(7-6-12-4-2-1-3-5-12)8-9-14-15-10-18(21)22-17(15)11-16(14)20/h1-5,13-17,19-20H,6-11H2/t13-,14+,15+,16+,17-/m0/s1 | | InChIKey | CQVHXVLSHMRWEC-UTSKFRMZSA-N | | SMILES | O1C(=O)C[C@]2([H])[C@@H](CC[C@@H](O)CCC3=CC=CC=C3)[C@H](O)C[C@]12[H] |
| | Latanoprost Lactone Diol Usage And Synthesis |
| Uses | (3aR,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]2H-cyclopenta[b]furan-2-one is phenyl-substituted prostaglandin and a potent and selective antiglaucoma agents. |
| | Latanoprost Lactone Diol Preparation Products And Raw materials |
| Raw materials | (-)-Corey lactone 4-phenylbenzoate alcohol-->[1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-5-phenyl-1-pentenyl]-2H-cyclopenta[b]furan-5-yl ester-->(3aR,4R,5R,6aS)-4-((R)-3-hydroxy-5-phenylpentyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate-->[1,1'-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl] -2-oxo-2H-cyclopenta[b]furan-5-yl ester-->HYDRIDE-L-->[1,1-Biphenyl]-4-carboxylic Acid (3aR,4R,5R,6aS)-Hexahydro-4-[(3R)-3-hydroxy-5-phenylpentyl]-2-oxo-2H-cyclopenta[b]furan-5-yl Ester-->Benzyl bromide | | Preparation Products | 1240483-21-9 |
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