|
|
| | SARAFOTOXIN S6B Basic information |
| Product Name: | SARAFOTOXIN S6B | | Synonyms: | M.W. 2564.00 C110H159N27O34S5;CYS-SER-CYS-LYS-ASP-MET-THR-ASP-LYS-GLU-CYS-LEU-TYR-PHE-CYS-HIS-GLN-ASP-VAL-ILE-TRP (DISULFIDE BRIDGE: CYS1-CYS15, CYS3-CYS11);Sarafotoxin 6b;Sarafotoxin S 6B (reduced), cyclic (1-15),(3-11)-bis(disulfide);Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Tyr-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11);Sarafotoxin B|SARAFOTOXIN S6B;CSCKDMTDKECLYFCHQDVIW;CYS-SER-CYS-LYS-ASP-MET-THR-ASP-LYS-GLU-CYS-LEU-TYR-PHE-CYS-HIS-GLN-ASP-VAL-ILE-TRP | | CAS: | 120972-53-4 | | MF: | C110H159N27O34S5 | | MW: | 2563.93 | | EINECS: | | | Product Categories: | Endothelin receptor | | Mol File: | 120972-53-4.mol |  |
| | SARAFOTOXIN S6B Chemical Properties |
| Boiling point | 2570.1±65.0 °C(Predicted) | | density | 1.298±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | Sequence | Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Tyr-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11) |
| | SARAFOTOXIN S6B Usage And Synthesis |
| Uses | Sarafotoxin S6b is a vasoconstrictor peptide, and a non-selective endothelin receptor agonist. Sarafotoxin S6b can induce contraction in isolated human coronary arteries , the Ki values of Coronary artery, Saphenous vein and Coronary artery are 0.27, 0.55 and 19.5 nM, respectively[1]. | | References | [1] P S Devadason et al. Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br J Pharmacol. 1997 May;121(2):253-63. DOI:10.1038/sj.bjp.0701126 |
| | SARAFOTOXIN S6B Preparation Products And Raw materials |
|