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| | Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 Basic information |
| Product Name: | Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 | | Synonyms: | Ac-AE-Asp(EDANS)-EE-Abu-L-lactoyl-S-Lys(DABCYL)-NH2;Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 ammonium salt;N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-(2S)-2-aminobutanoyl-(2S)-2-hydroxypropanoyl-L-seryl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysinamide;L-Lysinamide, N-acetyl-L-α-aspartyl-L-α-glutamyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-(2S)-2-aminobutanoyl-(2S)-2-hydroxypropanoyl-L-seryl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-;Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 | | CAS: | 188530-20-3 | | MF: | C68H89N15O25S | | MW: | 1548.59 | | EINECS: | | | Product Categories: | | | Mol File: | 188530-20-3.mol |  |
| | Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 Chemical Properties |
| density | 1.49±0.1 g/cm3(Predicted) | | pka | -0.26±0.40(Predicted) | | Sequence | Ac-Asp-Glu-{Asp(Edans)}-Glu-Glu-Abu-{ψ-(COO)Ala}-Ser-{Lys(Dabcyl)}-NH2 |
| | Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 Usage And Synthesis |
| Uses | Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM. Upon cleavage of this substrate, fluorescence can be monitored at Abs/Em = 355/500 nm.) |
| | Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 Preparation Products And Raw materials |
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