HIF-2α-IN-9 manufacturers
- HIF-2α-IN-9
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- $3100.00
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2026-05-11
- CAS:2648334-36-3
- Purity:
- Supply Ability: 10g
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| | HIF-2α-IN-9 Basic information |
| Product Name: | HIF-2α-IN-9 | | Synonyms: | HIF-2α-IN-9;4H-Cyclopenta[c]thiophene-4-ol, 5,5-difluoro-5,6-dihydro-3-(methylsulfonyl)-1-[(2S)-3,3,3-trifluoro-2-methylpropoxy]-, (4S)- | | CAS: | 2648334-36-3 | | MF: | C12H13F5O4S2 | | MW: | 380.35 | | EINECS: | | | Product Categories: | | | Mol File: | 2648334-36-3.mol |  |
| | HIF-2α-IN-9 Chemical Properties |
| Boiling point | 480.515±45.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.572±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 10.717±0.40(predicted) |
| | HIF-2α-IN-9 Usage And Synthesis |
| Uses | HIF-2α-IN-9 (compound 35r) is an inhibitor ofHIF-2α. HIF-2α-IN-9 inhibits VEGF-A (IC50=305 nM), and regulates growth-promoting genes in tumor cells, reactivates macrophage-mediated tumor immunity[1]. | | References |
[1] Buchstaller H P, et al. Discovery of Cycloalkyl [c] thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2 Inhibitors[J]. Journal of Medicinal Chemistry, 2023..
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| | HIF-2α-IN-9 Preparation Products And Raw materials |
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