|
|
| | AC-DELTA-ENDORPHIN (HUMAN) Basic information |
| Product Name: | AC-DELTA-ENDORPHIN (HUMAN) | | Synonyms: | B-endorphin fragment 1-27;B-ENDORPHIN FRAGMENT 1-27, HUMAN;BETA-ENDORPHIN, FRAGMENT 1-27;fragment1-27;β-endorphin human fragment 1-27;beta-endorphin, human, fragment 1-27;ACETYL, BETA-ENDORPHIN (1-27), HUMAN;ACETYL-TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-PHE-LYS-ASN-ALA-ILE-ILE-LYS-ASN-ALA-TYR-OH | | CAS: | 76622-84-9 | | MF: | C139H217N33O40S | | MW: | 3022.47 | | EINECS: | | | Product Categories: | Endorphins;Opioid Peptides;Peptides for Cell Biology | | Mol File: | 76622-84-9.mol |  |
| | AC-DELTA-ENDORPHIN (HUMAN) Chemical Properties |
| storage temp. | −20°C | | Sequence | Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr |
| | AC-DELTA-ENDORPHIN (HUMAN) Usage And Synthesis |
| Uses | β-Endorphin (1-27) (human) is an opioid antagonist that binds μ-, δ-, and κ-opioid receptors with Kis of 5.31, 6.17, and 39.82 nM, respectively. β-Endorphin (1-27) (human) inhibits β-Endorphin (HY-P1502)-induced and etorphine-induced analgesia[1][2]. | | References | [1] Mansour A, et al. The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. Brain Res. 1995 Nov 27;700(1-2):89-98. DOI:10.1016/0006-8993(95)00928-j
[2] Nicolas P, et al. Beta-endorphin-(1-27) is a naturally occurring antagonist to etorphine-induced analgesia. Proc Natl Acad Sci U S A. 1985 May;82(10):3178-81. DOI:10.1073/pnas.82.10.3178 |
| | AC-DELTA-ENDORPHIN (HUMAN) Preparation Products And Raw materials |
|