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| | Met-enkephalinamide Basic information |
| Product Name: | Met-enkephalinamide | | Synonyms: | 5-Methionine-enkephalin amide;L-Methioninamide, L-tyrosylglycylglycyl-L-phenylalanyl-;Lacosamide Impurity 61 | | CAS: | 60117-17-1 | | MF: | C27H36N6O6S | | MW: | 572.68 | | EINECS: | | | Product Categories: | | | Mol File: | 60117-17-1.mol |  |
| | Met-enkephalinamide Chemical Properties |
| Melting point | 142-145 °C | | Boiling point | 1066.7±65.0 °C(Predicted) | | density | 1.303±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.97±0.15(Predicted) | | Sequence | Tyr-Gly-Gly-Phe-Met-NH2 |
| | Met-enkephalinamide Usage And Synthesis |
| Uses | [Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors. | | IC 50 | δ Opioid Receptor/DOR | | References | [1] Stiene-Martin A, et al. Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro. J Neurosci Res. 1991 Aug;29(4):538-48. DOI:10.1002/jnr.490290415
[2] Kennedy C, et al. [Met5]enkephalin acts via delta-opioid receptors to inhibit pelvic nerve-evoked contractions of cat distal colon. Br J Pharmacol. 1987 Oct;92(2):291-8. DOI:10.1111/j.1476-5381.1987.tb11323.x |
| | Met-enkephalinamide Preparation Products And Raw materials |
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