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2,6-DIMETHOXYANILINE

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CAS:2734-70-5
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Products Intro: Product Name:2,6-DIMETHOXYANILINE
CAS:2734-70-5
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2,6-DIMETHOXYANILINE manufacturers

  • 2,6-DIMETHOXYANILINE
  • 2,6-DIMETHOXYANILINE  pictures
  • $1.10
  • 2026-08-20
  • CAS:2734-70-5
  • Min. Order: 1g
  • Purity: 99.00%
  • Supply Ability: 100 Tons Min
2,6-DIMETHOXYANILINE Basic information
Product Name:2,6-DIMETHOXYANILINE
Synonyms:2,6-DIMETHOXYANILINE;BUTTPARK 33\04-69;2,6-Dimethoxyaniline 98%;2,6-Dimethoxyaniline ,98%;2,6-Dimethoxy-phenylamine;2,6-dimethoxybenzenamine;NSC 43758;BenzenaMine, 2,6-diMethoxy-
CAS:2734-70-5
MF:C8H11NO2
MW:153.18
EINECS:206-719-8
Product Categories:Anilines, Aromatic Amines and Nitro Compounds
Mol File:2734-70-5.mol
2,6-DIMETHOXYANILINE Structure
2,6-DIMETHOXYANILINE Chemical Properties
Melting point 71-74
Boiling point 254℃
density 1.096
refractive index 1.4770 (estimate)
Fp 116℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form powder to crystal
pka4.48±0.10(Predicted)
color White to Gray to Brown
Water Solubility Slightly soluble in water.
InChIInChI=1S/C8H11NO2/c1-10-6-4-3-5-7(11-2)8(6)9/h3-5H,9H2,1-2H3
InChIKeyHQBJSEKQNRSDAZ-UHFFFAOYSA-N
SMILESC1(N)=C(OC)C=CC=C1OC
CAS DataBase Reference2734-70-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,T
Risk Statements 20/21/22-36/37/38-36-33
Safety Statements 26-36/37/39-36/37-28
RIDADR UN2811
Hazard Note Toxic/Irritant
TSCA N
HazardClass 6.1
PackingGroup III
HS Code 29214200
MSDS Information
2,6-DIMETHOXYANILINE Usage And Synthesis
Chemical PropertiesOff-white solid
Uses2,6-Dimethylaniline degradation by Fenton process has been studied in depth for the purpose of learning more about the reactions involved in the oxidation of 2,6-dimethylaniline under various reaction conditions. Using a previously developed gas chromatographic-mass spectrometric assay, hemoglobin adducts of 2,6-dimethylaniline were detected covalently bound to rat hemoglobin after administration of either 2,6-dimethylaniline or lidocaine.
Synthesis
Benzamide, N-hydroxy-2,6-dimethoxy-

51410-99-2

2,6-DIMETHOXYANILINE

2734-70-5

N-hydroxy-2,6-dimethoxybenzamide (1a) (0.237 g, 1.2 mmol) was used as a raw material and it was mixed with K2CO3 (0.166 g, 1.2 mmol) and DMSO (0.5 mL). Acetic anhydride (1.1 mL, 0.012 mmol) was added to the mixture and the reaction system was heated to 50°C. After stirring the reaction at this temperature for 10 min, the reaction mixture was cooled to 0°C and subsequently treated with 2M HCl (~2 mL). After the mixture was transformed into a clarified solution, it was neutralized by the addition of 2M NaOH (ca. 2 mL) and subsequently extracted with ether (Et2O, 15 mL x 3). The organic layers were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ether, 1:1) to afford the target product 2,6-dimethoxyaniline (2a) (0.171 g, 93% yield) as a white crystalline solid.

References[1] Chemical Communications, 2009, # 17, p. 2281 - 2283
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 38, p. 9046 - 9054
[3] Tetrahedron Letters, 2015, vol. 56, # 5, p. 710 - 712
Tag:2,6-DIMETHOXYANILINE(2734-70-5) Related Product Information
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