|
|
| | 3-Oxoolean-12-en-28-oic acid methyl ester Basic information |
| Product Name: | 3-Oxoolean-12-en-28-oic acid methyl ester | | Synonyms: | 3-Oxoolean-12-en-28-oic acid methyl ester;methyl 3-oxooleanolate;agonist,oleanolic acid derivative,PPAR,Methyl oleanonate,Inhibitor,MCF-7,HeLa,inhibit,Peroxisome proliferator-activated receptors,PPARγ,Anticancer effect;Olean-12-en-28-oic acid, 3-oxo-, methyl ester;Methyl oleanonate | | CAS: | 1721-58-0 | | MF: | C31H48O3 | | MW: | 468.71 | | EINECS: | | | Product Categories: | | | Mol File: | 1721-58-0.mol |  |
| | 3-Oxoolean-12-en-28-oic acid methyl ester Chemical Properties |
| Melting point | 184 °C | | Boiling point | 523.9±50.0 °C(Predicted) | | density | 1.06±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | Solid | | color | White to off-white |
| | 3-Oxoolean-12-en-28-oic acid methyl ester Usage And Synthesis |
| Uses | Methyl oleanonate is a natural triterpene PPARγ agonist isolated from the species of Pistacia lentiscus var. Chia[1]. Methyl oleanonate is a modified oleanolic acid derivative with anti-cancer effects[2]. | | IC 50 | PPARγ | | References | [1] Rasmus K Petersen, et al. Pharmacophore-driven identification of PPARγ agonists from natural sources. J Comput Aided Mol Des. 2011 Feb;25(2):107-16. DOI:10.1007/s10822-010-9398-5
[2] Barbara Bednarczyk-Cwynar, et al. Anticancer effect of A-ring or/and C-ring modified oleanolic acid derivatives on KB, MCF-7 and HeLa cell lines. Org Biomol Chem. 2012 Mar 21;10(11):2201-5 DOI:10.1039/c2ob06923g |
| | 3-Oxoolean-12-en-28-oic acid methyl ester Preparation Products And Raw materials |
|