4,7-二羟基-2-甲氧基-9,10-二氢菲
| 中文名称 | 4,7-二羟基-2-甲氧基-9,10-二氢菲 |
|---|---|
| 中文同义词 | 4,7-二羟基-2-甲氧基-9,10-二氢菲;4,7-二羟基-2-甲氧基-9,10-二氢菲,10 MM DMSO 溶液 |
| 英文名称 | 7-Methoxy-9,10-dihydrophenanthrene-2,5-diol |
| 英文同义词 | 7-Methoxy-9,10-dihydrophenanthrene-2,5-diol;9,10-Dihydro-2-methoxyphenanthrene-4,7-diol;4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene;2,5-Phenanthrenediol, 9,10-dihydro-7-methoxy-;Lusianthridin,Myc,Inhibitor,c-Myc,inhibit;Lusianthridin, 10 mM in DMSO;Lusianthridin |
| CAS号 | 87530-30-1 |
| 分子式 | C15H14O3 |
| 分子量 | 242.27 |
| EINECS号 | |
| 相关类别 | 对照品;其它酚类;标准品，对照品 |
| Mol文件 | 87530-30-1.mol |
| 结构式 |  |
4,7-二羟基-2-甲氧基-9,10-二氢菲 性质
| 沸点 | 507.3±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.296±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。 |
| 形态 | 粉末 |
| 酸度系数(pKa) | 9.23±0.20(Predicted) |
| 颜色 | 白色至米白色 |
Lusianthridin 是来自 Dendrobium venustum 的天然化合物，具有抗迁移作用。Lusianthridin 通过抑制Src-STAT3 信号，促进c-Myc 的降解。
Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively.
Cell Viability Assay
| Cell Line: | The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells [1] . 0-100 μM. |
| Concentration: | 0-100 μM. |
| Incubation Time: | 24 h. |
| Result: | Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells. |
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-121418 | 4,7-二羟基-2-甲氧基-9,10-二氢菲 Lusianthridin | 87530-30-1 | 1 mg | 1562元 |
| 2026/06/05 | HY-121418 | 4,7-二羟基-2-甲氧基-9,10-二氢菲 Lusianthridin | 87530-30-1 | 5mg | 3876元 |