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| | 5-Methoxygramine Basic information |
| | 5-Methoxygramine Chemical Properties |
| Melting point | 123-126 °C (lit.) | | Boiling point | 342.77°C (rough estimate) | | density | 1.0565 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | Refrigerator (+4°C) | | pka | 16.70±0.30(Predicted) | | BRN | 170533 | | InChI | 1S/C12H16N2O/c1-14(2)8-9-7-13-12-5-4-10(15-3)6-11(9)12/h4-7,13H,8H2,1-3H3 | | InChIKey | GOERTRUXQHDLHC-UHFFFAOYSA-N | | SMILES | COc1ccc2[nH]cc(CN(C)C)c2c1 | | CAS DataBase Reference | 16620-52-3(CAS DataBase Reference) |
| Hazard Codes | C,Xi | | Risk Statements | 34-22 | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | NL7700000 | | F | 10 | | HS Code | 29339900 | | Storage Class | 11 - Combustible Solids | | Toxicity | mouse,LD50,intraperitoneal,130mg/kg (130mg/kg),Psychopharmacologia Vol. 16, Pg. 385, 1970. |
| | 5-Methoxygramine Usage And Synthesis |
| Chemical Properties | white to almost white crystalline powder | | Uses | • ;Reactant for preparation of dopamine D2 receptor antagonists1• ;Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction2• ;Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands3• ;Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents4• ;Reactant for preparation of in | | Uses | - Reactant for preparation of dopamine D2 receptor antagonists
- Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
- Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
- Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
- Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives
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| | 5-Methoxygramine Preparation Products And Raw materials |
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