Biotin-PEG3-N3 manufacturers
- Biotin-PEG2-azide
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2025-06-07
- CAS:945633-30-7
- Min. Order: 250mg
- Purity: >98.00%
- Supply Ability: 250mg
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| | Biotin-PEG3-N3 Basic information |
| Product Name: | Biotin-PEG3-N3 | | Synonyms: | Biotin-PEG3-N3;1H-Thieno[3,4-d]imidazole-4-pentanamide,N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]hexahydro-2-oxo-,(3aS,4S,6aR)-;(+)-Biotin-PEG3- CH2CH2azide;(3aS,4S,6aR)-N-[2-[2-(2-Azidoethoxy)ethoxy]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;(+)-BIOTIN-PEG3-AZIDE;(+)-Biotin-PEG3-azide;(+)-Biotin-PEG2-azide;(+)-BIOTIN-PEG2-AZIDE | | CAS: | 945633-30-7 | | MF: | C16H28N6O4S | | MW: | 400.5 | | EINECS: | | | Product Categories: | SiChem;peg | | Mol File: | 945633-30-7.mol |  |
| | Biotin-PEG3-N3 Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | Solid | | color | White to off-white | | Appearance | colorless solid |
| | Biotin-PEG3-N3 Usage And Synthesis |
| Description | Biotin-PEG2-azide is a click chemistry biotinylation reagent. The azide group enable Click Chemistry reaction with alkyne, DBCO, BCN or prppargyl moiety to form a stable triazole linkage. | | Uses | Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG2-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Biotin-PEG3-N3 Preparation Products And Raw materials |
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