Biotin-PEG4-Azide manufacturers
- Biotin-PEG4-azide
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- $66.00 / 25mg
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2025-07-14
- CAS:1309649-57-7
- Min. Order:
- Purity: 99.09%
- Supply Ability: 10g
- Biotin-PEG4-azide
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- $0.00 / 100mg
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2025-06-07
- CAS:1309649-57-7
- Min. Order: 100mg
- Purity: >98.00%
- Supply Ability: 100mg
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| | Biotin-PEG4-Azide Basic information |
| Product Name: | Biotin-PEG4-Azide | | Synonyms: | N-(14-Azido-3,6,9,12-tetraoxatetradecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;(+)-Biotin-PEG4-CH2CH2N3;Biotin-PEG4-azide,Biotin-PEG4-N3;N-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide;Biotin-PEG4-CH2CH2N3/1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(14-azido-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)- | | CAS: | 1309649-57-7 | | MF: | C20H36N6O6S | | MW: | 488.60144 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1309649-57-7.mol |  |
| | Biotin-PEG4-Azide Chemical Properties |
| Melting point | 102.0 to 106.0 °C | | storage temp. | -20°C, sealed storage, away from moisture | | form | powder to lump | | color | White to Light yellow | | InChIKey | PVEHVEYAPUNCCP-LLFBLNAENA-N | | SMILES | C(NCCOCCOCCOCCOCCN=[N+]=[N-])(=O)CCCC[C@H]1[C@@]2([H])NC(=O)N[C@@]2([H])CS1 |&1:24,25,31,r| |
| | Biotin-PEG4-Azide Usage And Synthesis |
| Description | Biotin-PEG4-azide is a very useful biotinylation reagent that enable Click Chemistry reaction with alkyne, such as Propargyl, DBCO or BCN reagent to form a stable bond. PEG4 spacer increases aqueous solubility of the molecules conjugated to the biotin. It also helps to minimize steric hindrance involved with the binding to avidin molecules. | | Uses | Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329 |
| | Biotin-PEG4-Azide Preparation Products And Raw materials |
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