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N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid

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Company Name: CONIER CHEM AND PHARMA LIMITED
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Products Intro: Product Name:n-(((4-methoxyphenyl)thio)carbonyl)-l-glutamic acid
CAS:192203-60-4
Purity:0.99 Package:1kg
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Products Intro: Product Name:N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid
CAS:192203-60-4
Purity:>=98% Package:1g;1USD
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Carboxypeptidase G2 (CPG2) Inhibitor
CAS:192203-60-4
Purity:99.69% Package:1mg;48USD|5mg;113USD|10mg;179USD Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid
CAS:192203-60-4
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Carboxypeptidase G2 (CPG2) Inhibitor
CAS:192203-60-4
Purity:99.69% Package:1mg;48USD|5mg;113USD|10mg;179USD

N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid manufacturers
N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid Basic information
Product Name:N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid
Synonyms:N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid;Carboxypeptidase G2 (CPG2) Inhibitor;CPG2 Inhibitor;L-GlutaMic acid, N-[[(4-Methoxyphenyl)thio]carbonyl]-;Carboxypeptidase G2 Inhibitor;CPG2 INHIBITOR;L-GLUTAMIC ACID; N-[[(4-METHOXYPHENYL)THIO]CARBONYL]-;N-[[(4-methoxyphenyl)thio]carbonyl]-;(2S)-2-[(4-methoxyphenyl)sulfanylcarbonylamino]pentanedioicaci
CAS:192203-60-4
MF:C13H15NO6S
MW:313.33
EINECS:
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Mol File:192203-60-4.mol
N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid Structure
N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid Chemical Properties
density 1.43
storage temp. Store at -20°C
solubility H2O : 1.43 mg/mL (4.56 mM; Need ultrasonic)
form Powder
pka3.41±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid Usage And Synthesis
UsesCarboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
References[1] Khan, Tariq H.; Eno-Amooquaye, Ebun A.; Searle, Frances et al. Novel Inhibitors of Carboxypeptidase G2 (CPG2): Potential Use in Antibody-Directed Enzyme Prodrug Therapy. Journal of Medicinal Chemistry (1999), 42(6), 951-956. DOI:10.1021/jm990004i
[2] Friedlos F, Lehouritis P, Ogilvie L et al. Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy. Clin Cancer Res. 2008 Jul 1;14(13):4259-66. DOI:10.1158/1078-0432.CCR-07-4800
[3] Schepelmann S, Ogilvie LM, Hedley D et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007 May 15;67(10):4949-55. DOI:10.1158/0008-5472.CAN-07-0297
[4] Schepelmann S, Hallenbeck P, Ogilvie LM et al. Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2. Cancer Res. 2005 Jun 15;65(12):5003-8. DOI:10.1158/0008-5472.CAN-05-0393
N-[[(4-Methoxyphenyl)thio]carbonyl]-L-glutamic acid Preparation Products And Raw materials
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