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| | Kushenol L Basic information |
| Product Name: | Kushenol L | | Synonyms: | Kushenol L;product/154902;4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-, (2R,3R)-;(2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one | | CAS: | 101236-50-4 | | MF: | C25H28O7 | | MW: | 440.49 | | EINECS: | | | Product Categories: | | | Mol File: | 101236-50-4.mol |  |
| | Kushenol L Chemical Properties |
| Boiling point | 715.7±60.0 °C(Predicted) | | density | 1.334±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Cryst. | | pka | 8.04±0.60(Predicted) |
| | Kushenol L Usage And Synthesis |
| Uses | Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects[1]. | | in vivo | Kushenol L (1 mg/kg; oral) has a T1/2 of 2.26 hours, a Cmax of 24.17 μg/L and an AUC of 54035 μg/hL in adult male Sprague-Dawley rats weighing 300 g[1].
| | References | [1] Lei Chen, et al. An accurate and reproducible method for simultaneous determination of four flavonoids in EtOAc extracts from Sophora flavescens Ait. in rat plasma based on UHPLC Q-Exactive Mass spectrometry: Application to a pharmacokinetics study. Biomed Chromatogr. 2019 Mar;33(3):e4447. DOI:10.1002/bmc.4447 |
| | Kushenol L Preparation Products And Raw materials |
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