4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)- manufacturers
- Kushenol E
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- $261.00
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2026-07-27
- CAS:99119-72-9
- Purity:
- Supply Ability: 10g
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| | 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)- Basic information |
| Product Name: | 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)- | | Synonyms: | 4H-1-Benzopyran-4-one,2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-,(2S)-;4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)-;(2S)-2-(2,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;flemiphilippinin D;4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)- USP/EP/BP;Kushenol E | | CAS: | 99119-72-9 | | MF: | C25H28O6 | | MW: | 424.49 | | EINECS: | | | Product Categories: | | | Mol File: | 99119-72-9.mol |  |
| | 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)- Chemical Properties |
| storage temp. | 4°C, away from moisture and light | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Cryst. | | color | Off-white to light yellow |
| | 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)- Usage And Synthesis |
| Chemical Properties | Pale yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from the creeping Ficus microcarpa F. philippinensis. | | Uses | Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 of 7.7μM and a Ki of 9.5μM, has anti-tumor activity[1]. | | target | NF-kB | ROS | | References | [1] Kwon M, et al. Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488. DOI:10.1080/14756366.2019.1640218 |
| | 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydro xy-6,8-bis(3-methyl-2-butenyl)-, (S)- Preparation Products And Raw materials |
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