| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
- GRK2 Inhibitor
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- $135.00
-
2026-05-11
- CAS:24269-96-3
- Purity: 98.46%
- Supply Ability: 10g
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| | 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Basic information |
| | 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Chemical Properties |
| Melting point | 139-140 °C | | Boiling point | 408.4±45.0 °C(Predicted) | | density | 1.400±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Acetone (Slightly), Methanol (Slightly) | | form | Solid | | color | Pale Yellow to Yellow | | Sensitive | Light Sensitive | | InChI | 1S/C12H9NO6/c1-17-12(14)10-6-4-8(18-10)2-3-9-5-7-11(19-9)13(15)16/h2-7H,1H3/b3-2+ | | InChIKey | YDJPHSNZGRVPCK-NSCUHMNNSA-N | | SMILES | [N+](=O)([O-])c1[o]c(cc1)\C=C\c2[o]c(cc2)C(=O)OC |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Usage And Synthesis |
| Uses | 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction. | | Biological Activity | Cell permeable: no', 'Primary Target
βARK1 (β-Adrenergic Receptor Kinase 1)', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 126 μM against βARK1 (β-Adrenergic Receptor Kinase 1) |
| | 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Preparation Products And Raw materials |
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