| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Company Name: |
SPIRO PHARMA |
| Tel: |
|
| Email: |
eric_feng1954@126.com |
| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
NVS-CRF38 manufacturers
- NVS-CRF38
-
- $2180.00
-
2026-05-11
- CAS:1207258-55-6
- Purity:
- Supply Ability: 10g
- NVS-CRF38
-
- $2180.00
-
2025-07-31
- CAS:1207258-55-6
- Purity:
- Supply Ability: 10g
|
| | NVS-CRF38 Basic information |
| Product Name: | NVS-CRF38 | | Synonyms: | NVS-CRF38;Pyrazolo[5,1-b]oxazole, 7-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethyl-;NVS CRF38,NVSCRF38,NVS-CRF-38 | | CAS: | 1207258-55-6 | | MF: | C19H21N5O2 | | MW: | 351.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1207258-55-6.mol |  |
| | NVS-CRF38 Chemical Properties |
| density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 2.58±0.50(Predicted) |
| | NVS-CRF38 Usage And Synthesis |
| Uses | NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.
IC50 value:
Target: CRF1 antagonist | | References | [1] Stringer RA, et al. Preclinical metabolism and pharmacokinetics of NVS-CRF38, a potent and orally bioavailable corticotropin-releasing factor receptor 1 antagonist. Xenobiotica. 2014 Apr 3. DOI:10.3109/00498254.2014.907458
[2] Stringer RA, et al. 1-Aminobenzotriazole modulates oral drug pharmacokinetics through cytochrome P450 inhibition and delay of gastric emptying in rats. Drug Metab Dispos. 2014 Jul;42(7):1117-24. DOI:10.1124/dmd.113.056408 |
| | NVS-CRF38 Preparation Products And Raw materials |
|