2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid

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2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid manufacturers

  • DGAT1-IN-1
  • DGAT1-IN-1 pictures
  • $56.00
  • 2026-07-27
  • CAS:1449779-49-0
  • Purity: 99.15%
  • Supply Ability: 10g
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Basic information
Product Name:2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
Synonyms:2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid;DGAT1-IN-1;CS-2654;CS-2804;DGAT1 inhibitor 1;Cyclohexaneacetic acid, 4-[4-[2-[[[[4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]imidazo[1,2-a]pyridin-6-yl]phenyl]-, trans-;Diacylglycerol acyltransferase,inhibit,Acyltransferase,mono- acylglycerol acyltransferase,Inhibitor,DGAT1 IN 1,Diglyceride acyltransferase,acyl-CoA:cholesterol acyltransferase,DGAT-1-IN-1,DGAT1IN1;rel-2-((1r,4r)-4-(4-(2-((4-(Trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
CAS:1449779-49-0
MF:C30H28F3N3O4
MW:551.56
EINECS:
Product Categories:
Mol File:1449779-49-0.mol
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Structure
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Chemical Properties
density 1.36±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 20 mg/mL (36.26 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Powder
pka4.72±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Usage And Synthesis
UsesDGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1). IC50 value: < 10 nM Target: DGAT1 inhibitor Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation By Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.
References[1] Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme , Patent: WO 2013119040 A1
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Preparation Products And Raw materials
Tag:2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid(1449779-49-0) Related Product Information
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