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| | Anti-Docking protein CAIR-1 Basic information |
| Product Name: | Anti-Docking protein CAIR-1 | | Synonyms: | Anti-BAG3 antibody produced in rabbit;Anti-BAG3 (C-terminal) antibody produced in goat;Anti-BAG-3;Anti-BAG family molecular chaperone regulator 3;Anti-Bcl-2-associated athanogene 3;Anti-Bcl-2-binding protein Bis;Anti-Docking protein CAIR-1;BCL2-associated athanogene 3 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-Docking protein CAIR-1 Structure]() |
| | Anti-Docking protein CAIR-1 Chemical Properties |
| storage temp. | -20°C | | form | liquid | | biological source | rabbit |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | WGK 1 | | Storage Class | 12 - Non Combustible Liquids |
| | Anti-Docking protein CAIR-1 Usage And Synthesis |
| Uses | Detect BAG3 using this chicken polyclonal Anti-BAG3 Antibody, validated for use in Western Blotting.
Research Category
Apoptosis & Cancer | | Biological Activity | BAG3 inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. BAG3 has anti-apoptotic activity.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Publication Note: This RefSeq record includes a subset of the publications th at are available for this gene. Please see the Entrez Gene record to access additional publications. |
| | Anti-Docking protein CAIR-1 Preparation Products And Raw materials |
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