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| | (D-ALA4)-SUBSTANCE P (4-11) Basic information |
| Product Name: | (D-ALA4)-SUBSTANCE P (4-11) | | Synonyms: | D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2;(D-ALA4)-SUBSTANCE P (4-11);H-D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2;SUBSTANCE P OCTAPEPTIDE D-ALA-4-FRAGMENT 4-11);Substance P, fragment 4-11, (D-Ala4);(2S)-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]-2-[[(2R)-2-aminopropanoyl]amino]pentanediamide;Substance P,1-de-L-arginine-2-de-L-proline-3-de-L-lysine-4-D-alanine-;Substance P,1-de-L-arginine-2-de-L-proline-3-de-L-lysine-4-D-alanine- (9CI) | | CAS: | 81381-50-2 | | MF: | C44H65N11O10S | | MW: | 940.12 | | EINECS: | | | Product Categories: | | | Mol File: | 81381-50-2.mol |  |
| | (D-ALA4)-SUBSTANCE P (4-11) Chemical Properties |
| Boiling point | 1450.5±65.0 °C(Predicted) | | density | 1.265±0.06 g/cm3(Predicted) | | storage temp. | -15°C | | pka | 13.26±0.46(Predicted) |
| | (D-ALA4)-SUBSTANCE P (4-11) Usage And Synthesis |
| Uses | [DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1]. | | References | [1] M A Cascieri, et al. Demonstration of two distinct tachykinin receptors in rat brain cortex. J Biol Chem. 1985 Feb 10;260(3):1501-7. PMID:2578461 |
| | (D-ALA4)-SUBSTANCE P (4-11) Preparation Products And Raw materials |
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