N-Boc-N-bis(PEG3-OH) manufacturers
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| | N-Boc-N-bis(PEG3-OH) Basic information |
| Product Name: | N-Boc-N-bis(PEG3-OH) | | Synonyms: | N-Boc-N-(PEG3-OH)2;N-Boc-N-bis(PEG3-OH);5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester;BocN-(PEG4-OH)2;tert-Butyl bis(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)carbamate | | CAS: | 2093154-01-7 | | MF: | C21H43NO10 | | MW: | 469.57 | | EINECS: | | | Product Categories: | | | Mol File: | 2093154-01-7.mol |  |
| | N-Boc-N-bis(PEG3-OH) Chemical Properties |
| Boiling point | 557.6±50.0 °C(Predicted) | | density | 1.120±0.06 g/cm3(Predicted) | | pka | 14.06±0.10(Predicted) |
| | N-Boc-N-bis(PEG3-OH) Usage And Synthesis |
| Description | N-Boc-N-bis(PEG3-OH) is a small molecule with two terminal hydroxy groups and a Boc protected amino group. The hydroxy groups can be derivatized or replaceedwith other reactive functional groups. N-Boc can be deprotected under acidic conditions. | | Uses | N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | | IC 50 | Cleavable Linker; PEGs; Alkyl/ether | | References | [1] Alain Wagner, et al. Intra-droplet surface engineering to capture a molecular target. WO2017174610A1. |
| | N-Boc-N-bis(PEG3-OH) Preparation Products And Raw materials |
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