Tri(carboxyethyloxyethyl)amine HCl salt

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Tri(carboxyethyloxyethyl)amine HCl salt Basic information
Product Name:Tri(carboxyethyloxyethyl)amine HCl salt
Synonyms:Tri(carboxyethyloxyethyl)amine HCl salt;Tri-(PEG1-C2-acid);Propanoic acid, 3,3',3''-[nitrilotris(2,1-ethanediyloxy)]tris-
CAS:1381861-95-5
MF:C15H27NO9
MW:365.38
EINECS:
Product Categories:
Mol File:1381861-95-5.mol
Tri(carboxyethyloxyethyl)amine HCl salt Structure
Tri(carboxyethyloxyethyl)amine HCl salt Chemical Properties
Boiling point 606.1±55.0 °C(Predicted)
density 1.275±0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO, DMF
pka3.76±0.10(Predicted)
Safety Information
MSDS Information
Tri(carboxyethyloxyethyl)amine HCl salt Usage And Synthesis
DescriptionTri(carboxyethyloxyethyl)amine HCl salt is a 3-arm branched molecule that can react with primary amino-containing entity in the presence of activator EDC or HATU
UsesTri-(PEG1-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Tri(carboxyethyloxyethyl)amine HCl salt Preparation Products And Raw materials
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5-Ethynyl-2'-deoxyuridine TCO-PEG4-NHS Ester Tranexamic Acid 15-hexadecynoic acid (S)-2-Aminohex-5-ynoic acid DBCO-PEG4-SE