GRF (1-29) amide (rat)

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GRF (1-29) amide (rat) Basic information
Product Name:GRF (1-29) amide (rat)
Synonyms:H-HIS-ALA-ASP-ALA-ILE-PHE-THR-SER-SER-TYR-ARG-ARG-ILE-LEU-GLY-GLN-LEU-TYR-ALA-ARG-LYS-LEU-LEU-HIS-GLU-ILE-MET-ASN-ARG-NH2;GROWTH HORMONE RELEASING FACTOR FRAGMENT 1-29 AMIDE RAT;GROWTH HORMONE-RELEASING FACTOR (1-29) AMIDE (RAT);GHRF (1-29), AMIDE, RAT;somatoliberin fragment 1-29 amide, rat;GRF(1-29)NH2【rat】;L-His-L-Ala-L-Asp-L-Ala-L-Ile-L-Phe-L-Thr-L-Ser-L-Ser-L-Tyr-L-Arg-L-Arg-L-Ile-L-Leu-Gly-L-Gln-L-Leu-L-Tyr-L-Ala-L-Arg-L-Lys-L-Leu-L-Leu-L-His-L-Glu-L-Ile-L-Met-L-Asn-L-Arg-NH2;Somatoliberin(1-29)amide[rat]
CAS:91826-20-9
MF:C155H251N49O40S
MW:3473.02
EINECS:
Product Categories:GH-RH;Peptides for Cell Biology;Releasing Factors
Mol File:91826-20-9.mol
GRF (1-29) amide (rat) Structure
GRF (1-29) amide (rat) Chemical Properties
density 1.46±0.1 g/cm3(Predicted)
storage temp. −20°C
form Solid
color White to off-white
SequenceHis-Ala-Asp-Ala-Ile-Phe-Thr-Ser-Ser-Tyr-Arg-Arg-Ile-Leu-Gly-Gln-Leu-Tyr-Ala-Arg-Lys-Leu-Leu-His-Glu-Ile-Met-Asn-Arg-NH2
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
GRF (1-29) amide (rat) Usage And Synthesis
UsesGRF (1-29) amide (rat) is a synthetic peptide which can stimulate the growth hormone (GH) secretion.
in vivo

Time course studies of GRF (1-29) amide (rat) disappearance show apparent half-lives of 18±4 min and 13±3 min in serum and liver homogenate, respectively. This is accompanied by the appearance of degradation products that are all less hydrophobic than the native peptide. In the serum, two major metabolites are detected and isolated by preparative HPLC[1].

References[1] Boulanger L, et al. Catabolism of rat growth hormone-releasing factor(1-29) amide in rat serum and liver. Peptides. 1992 Jul-Aug;13(4):681-9. DOI:10.1016/0196-9781(92)90173-z
GRF (1-29) amide (rat) Preparation Products And Raw materials
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