H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	18930552037
Email:	3bsc@sina.com

Company Name:	Shanghai Hanhong Scientific Co.,Ltd.
Tel:	021-54306202 13764082696
Email:	info@hanhongsci.com

Company Name:	Chemsky（shanghai）International Co.,Ltd.
Tel:	021-50135380
Email:	shchemsky@sina.com

H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH manufacturers

H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
$7.00
2020-02-14
CAS:123562-20-9
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg

H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
$7.00
2020-02-14
CAS: 123562-20-9
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg

H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH Basic information

Product Name:	H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH
Synonyms:	ET-2 (HUMAN);ET-2 (HUMAN, PIG, DOG);H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11);ENDOTHELIN-II, HUMAN;ENDOTHELIN 2;ENDOTHELIN 2 HUMAN;ENDOTHELIN-2 (HUMAN, CANINE);ENDOTHELIN-2 (HUMAN, PIG, DOG)
CAS:	123562-20-9
MF:	C115H160N26O32S4
MW:	2546.92
EINECS:
Product Categories:	Cardiovescular;Peptide;AgonistsApplication Index;Chymase and Related Products;Cell Signaling Enzymes;Endothelins;Peptides for Cell Biology;Endothelin receptor
Mol File:	123562-20-9.mol

H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH Chemical Properties

density	1.286±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
storage temp.	−20°C
solubility	Soluble to 1 mg/ml in DMSO
form	powder
color	white
Water Solubility	Soluble in water (1 mg/ml)
Sequence	Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH Usage And Synthesis

Uses	Endothelin-2 (49-69), human (Endothelin-2 (human, canine)) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
in vivo	Two distinct phases of pressor effects are typically seen in response to Endothelin-2: the early phase immediately follows the depressor response and dominates during the next 3-10 min, whereas the late pressor effect develops 10-20 min after the injection and lasts >1 hr^[1].
storage	-20°C (desiccate)
References	[1] Grimshaw MJ, et al. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol. 2002 Sep;32(9):2393-400. DOI:10.1002/1521-4141(200209)32:93.0.CO;2-4

H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH Preparation Products And Raw materials

Tag:H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH(123562-20-9) Related Product Information

Endothelin-1 (human, porcine) H-Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH Big ET-1 (1-38) (human) Endothelin (16-21) Nitric oxide IRL-1038 Serotonin hydrochloride HISTONE L(+)-Arginine Follicle stimulating hormone Histamine Luteinizing Hormone Prostaglandin E2 RENNIN Bilirubin Bacterial endotoxin Endothelin antagonist H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH