1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane

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1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane manufacturers

  • N3-PEG7-Br
  • N3-PEG7-Br pictures
  • 2026-07-24
  • CAS:1056969-61-9
  • Min. Order: 1g
  • Purity: 98%
  • Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
  • Azido-PEG7-Br
  • Azido-PEG7-Br pictures
  • 2025-06-07
  • CAS:1056969-61-9
  • Min. Order: 1g
  • Purity: >98.00%
  • Supply Ability: 1g
1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Basic information
Product Name:1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane
Synonyms:1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane;N3-PEG7-CH2CH2Br;N3-PEG7-CH2CH2Br/3,6,9,12,15,18,21-Heptaoxatricosane, 1-azido-23-bromo-
CAS:1056969-61-9
MF:C16H32BrN3O7
MW:458.35
EINECS:
Product Categories:
Mol File:1056969-61-9.mol
1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Structure
1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Chemical Properties
storage temp. 2-8°C, sealed storage, away from moisture
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Usage And Synthesis
UsesBromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Biological ActivityBromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50PEGs
References[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Preparation Products And Raw materials
Tag:1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane(1056969-61-9) Related Product Information
BocNH-PEG7-CH2CH2N3 Azido-PEG7-NHS ester Azide-PEG7-Tos Amino-PEG8-azide Azido-PEG8-acid Azido-PEG7-hydrazide Azido-PEG7-azide Azido-PEG7-COOtBu N3-PEG7-OH