Azide-PEG7-Tos manufacturers
- N3-PEG7-Tos
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2026-07-24
- CAS:1418561-41-7
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- Azido-PEG7-Tos
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2025-06-07
- CAS:1418561-41-7
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
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| | Azide-PEG7-Tos Basic information |
| Product Name: | Azide-PEG7-Tos | | Synonyms: | Azido-PEG7-OTs;Azide-PEG7-Tos;N3-PEG7-Tos;Azido-PEG7-Tos;N3-PEG7-Tos/3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-azido-, 1-(4-methylbenzenesulfonate);N3-PEG7-OTos;20-Azido-3,6,9,12,15,18-hexaoxaicosyl 4-methylbenzenesulfonate | | CAS: | 1418561-41-7 | | MF: | C21H35N3O9S | | MW: | 505.58 | | EINECS: | | | Product Categories: | | | Mol File: | 1418561-41-7.mol |  |
| | Azide-PEG7-Tos Chemical Properties |
| solubility | Soluble in DMSO, DCM, DMF |
| | Azide-PEG7-Tos Usage And Synthesis |
| Description | Azide-PEG7-Tos is a PEG linker containing an azide group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions. | | Uses | Azide-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG7-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Azide-PEG7-Tos Preparation Products And Raw materials |
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