ATR inhibitor 1 manufacturers
- Tuvusertib
-
- $56.00
-
2026-07-24
- CAS:1613200-51-3
- Purity: 98.44%
- Supply Ability: 10g
- Tuvusertib
-
- $56.00
-
2026-07-24
- CAS:1613200-51-3
- Purity: 98.44%
- Supply Ability: 10g
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| | ATR inhibitor 1 Basic information |
| Product Name: | ATR inhibitor 1 | | Synonyms: | ATR inhibitor 1;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)-3-pyridinyl]-;M-1774;M1774|||ATR inhibitor 1;Tuvusertib, 10 mM in DMSO;2-Amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;Tuvusertib | | CAS: | 1613200-51-3 | | MF: | C16H12F2N8O | | MW: | 370.32 | | EINECS: | | | Product Categories: | | | Mol File: | 1613200-51-3.mol |  |
| | ATR inhibitor 1 Chemical Properties |
| density | 1.68±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 6.48±0.46(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | ATR inhibitor 1 Usage And Synthesis |
| Uses | Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a Ki value below 1 μΜ[1]. | | References | [1] Nadia AHMAD, et al. Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, the preparation of said compound and different solid forms thereof. WO2015187451A1
[2] Lin Li, et al. Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells DOI:10.1007/s13402-023-00817-6 |
| | ATR inhibitor 1 Preparation Products And Raw materials |
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