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(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride

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(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Basic information
Product Name:(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
Synonyms:(R)-1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride;(R)-1-(7,8-dihydrophthalen-1-yl)ethan-1-amine hydrochloride;(R)-<1-(1-Naphthyl)ethyl>ammonium chloride;?-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE;(R)-(+)-1-(1-Naphthyl)ethylamine Hcl;(R)-(+)-1,1-Naphthyl ethylamine HCI;(R)-1-(naphthalen-1-yl)ethanaMine (Hydrochloride);1-Naphthalenemethanamine, alpha-methyl-, hydrochloride, (alphaR)-
CAS:82572-04-1
MF:C12H14ClN
MW:207.69926
EINECS:617-358-4
Product Categories:Miscellaneous;Amine Salts;Chiral Building Blocks;Organic Building Blocks
Mol File:82572-04-1.mol
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Structure
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Chemical Properties
Melting point 253-257 °C(lit.)
storage temp. Sealed in dry,Room Temperature
form solid
AppearanceWhite to off-white Solid
Optical Rotation[α]/D 5.2±2°, c = 1 in methanol
InChIInChI=1/C12H13N.ClH/c1-9(13)11-8-4-6-10-5-2-3-7-12(10)11;/h2-9H,13H2,1H3;1H/t9-;/s3
InChIKeyZTNKTVBJMXQOBQ-OVMXBOEKNA-N
SMILESC1(=CC=CC2C=CC=CC1=2)[C@@H](C)N.Cl |&1:10,r|
Safety Information
Hazard Codes Xn,N
Risk Statements 22-36/37/38-50
Safety Statements 26-60-61
RIDADR UN 3077 9 / PGIII
WGK Germany 2
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Aquatic Acute 1
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Usage And Synthesis
Uses(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is a pharmaceutical intermediate used in the preparation of cinacalcet hydrochloride, which treats secondary hyperparathyroidism due to chronic kidney disease. In addition, (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is also used in analytical assays. Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Preparation Products And Raw materials
Preparation ProductsN-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide
Tag:(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride(82572-04-1) Related Product Information
(R)-(+)-1-(1-Naphthyl)ethylamine (1R)-1-(5-methylnaphthalen-1-yl)ethan-1-amine (R)-1-(Naphthalen-2-yl)ethanamine hydrochloride Cinacalcet IMpurity 7 (E)-m-(trifluoromethyl)cinnamic acid Cinacalcet Impurity 38 HCl Cinacalcet Impurity B Cinacalcet IMpurity 3 Cinacalcet Impurity 46 Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester cinacalcet iMpurity 4 N-(1-(naphthalen-1-yl)ethyl)forMaMide Cinacalcet impurity C Cinacalcet Impurity 45 Cinacalcet Impurity 39 (Mixture of Diastereomers) 4-(Trifluoromethyl)hydrocinnamic acid 3-(4-Trifluoromethyl-phenyl)-propan-1-ol 1-Naphthalen-2-yl-ethylamine