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| | 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Basic information |
| Product Name: | 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% | | Synonyms: | 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%;Tacrine HCl hydrate;Cholinesterase (ChE),inhibit,Tacrine hydrochloride (hydrate),Inhibitor;Tacrine hydrochloride (hydrate), 10 mM in DMSO;1,2,3,4-Tetrahydroacridin-9-amine xhydrochloride xhydrate , Tacrine hydrochloride (hydrate);1,2,3,4-Tetrahydroacridin-9-amine xhydrochloride xhydrate;9-Acridinamine, 1,2,3,4-tetrahydro-, hydrochloride, hydrate | | CAS: | 206658-92-6 | | MF: | C13H17ClN2O | | MW: | 252.74 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | Mol File |  |
| | 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Chemical Properties |
| Melting point | 284-286°C (lit.) | | storage temp. | Store at -20°C | | solubility | H2O: soluble | | form | powder | | color | faint yellow | | Water Solubility | H2O: soluble | | InChI | 1S/C13H14N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H;1H2 | | InChIKey | PXGRMZYJAOQPNZ-UHFFFAOYSA-N | | SMILES | O.Cl.Nc1c2CCCCc2nc3ccccc13 |
| Hazard Codes | T | | Risk Statements | 23/24/25-36/37/38-40 | | Safety Statements | 22-24/25-26-36/37/39 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | HS Code | 2933998090 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Carc. 2
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Usage And Synthesis |
| Uses | 9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate is a well-known cholinesterase inhibitor commonly used in pharmacological studies. | | in vivo | Pretreatment with Tacrine hydrochloride (hydrate) also modifies absolute levels of cocaine self-administration during reacquisition. Body weight declines approximately one-half percent over four days of treatment with intravenous Tacrine hydrochloride (hydrate). Delivery of Tacrine hydrochloride (hydrate) by osmotic pump does not alter either linear- or repeated- cocaine-induced locomotor activity. There is no significant main effect or interaction with Tacrine hydrochloride (hydrate) treatment on active lever responding during reinstatement. Post hoc comparisons indicate that rats self-administering cocaine has significantly lower alkaline phosphatase levels, relative to TTacrine hydrochloride (hydrate)- but not saline- treated rats evaluated by conditioned-place preference[2]. | | IC 50 | AChE; BChE |
| | 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Preparation Products And Raw materials |
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