Cholic Acid anilide manufacturers
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| | Cholic Acid anilide Basic information |
| Product Name: | Cholic Acid anilide | | Synonyms: | Cholic Acid anilide;Cholan-24-amide, 3,7,12-trihydroxy-N-phenyl-, (3α,5β,7α,12α)-;(5β)-3α,7α,12α-trihydroxy-N-phenyl-cholan-24-amide | | CAS: | 6912-96-5 | | MF: | C30H45NO4 | | MW: | 483.69 | | EINECS: | | | Product Categories: | | | Mol File: | 6912-96-5.mol |  |
| | Cholic Acid anilide Chemical Properties |
| Boiling point | 673.1±55.0 °C(Predicted) | | density | 1.176±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml; Ethanol: 1 mg/ml | | form | A crystalline solid | | pka | 14.65±0.70(Predicted) |
| | Cholic Acid anilide Usage And Synthesis |
| Description | Cholic acid anilide is a synthetic bile acid and derivative of cholic acid that inhibits the germination of C. difficile strain R20291 spores in vitro (IC50 = 1.8 μM).1 | | Uses | Cholic acid anilide, a Narylcholan-24-amide, is a potent inhibitor of C. difficile spore germination with an IC50 value of 1.8 μM in the spore germination assay conducted in Sodium phosphate media containing 6 mM Taurocholate (HY-B1131) and 12 mM Glycine (HY-Y0966). Cholic acid anilide has the potential for C. difficile infections research[1]. | | References | 1. Sharma, S.K., Yip, C., Esposito, E.X., et al. The design, synthesis, and characterizations of spore germination inhibitors effective against an epidemic strain of Clostridium difficile J. Med. Chem. 61(15),6759-6778(2018). |
| | Cholic Acid anilide Preparation Products And Raw materials |
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