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| | 9(E),11(E)-9-nitro Conjugated Linoleic Acid Basic information |
| | 9(E),11(E)-9-nitro Conjugated Linoleic Acid Chemical Properties |
| Boiling point | 457.2±28.0 °C(Predicted) | | density | 1.016±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | 0.1M Na2CO3: 1mg/mL,DMF: 50mg/mL,DMSO: 50mg/mL,Ethanol: 50mg/mL | | pka | 4.77±0.10(Predicted) |
| | 9(E),11(E)-9-nitro Conjugated Linoleic Acid Usage And Synthesis |
| Uses | (9E,11E)-9-Nitro-9,11-octadecadienoic acid (9E,11E-9-Nitro CLA) is a nitro-fatty acid, It is formed by exposure of 9Z, 11E-CLA to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite[1]. | | Biological Activity | 9(E),11(E)-9-nitro Conjugated linoleic acid (9E,11E-9-nitro CLA) is a nitrated fatty acid. It is formed from 9Z,11E-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1 It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .2 9E,11E-9-nitro CLA has been found in human plasma. | | References | 1.Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al.Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienesJ. Org. Chem.79(1)25-33(2014)
2.Bonacci, G., Baker, P.R.S., Salvatore, S.R., et al.Conjugated linoleic acid is a preferential substrate for fatty acid nitrationJ. Biol. Chem.287(53)44071-44082(2012) |
| | 9(E),11(E)-9-nitro Conjugated Linoleic Acid Preparation Products And Raw materials |
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