9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

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9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) manufacturers
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Basic information
Product Name:9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
Synonyms:9(Z),11(E)-Conjugated Linoleic Acid (sodium salt);11(E)-CLA;(9Z,11E)-9,11-octadecadienoic acid, monosodium salt
CAS:756499-04-4
MF:C18H33NaO2
MW:304.45
EINECS:
Product Categories:
Mol File:756499-04-4.mol
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Structure
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Chemical Properties
storage temp. Store at -20°C
solubility DMSO: soluble; Methanol: soluble; Water: soluble
form A solid
Safety Information
MSDS Information
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Usage And Synthesis
UsesBovinic acid sodium is a fatty acid (FA) extracted from the Indonesian coix seed (C. lacryma-jobi) variety Agrotis. Bovinic acid sodium is an insecticide with inhibitory activity against Leptinotarsa decemlineata[1].
Biological Activity9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1 It binds to peroxisome proliferator-activated receptor α (PPARα; IC50 = 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.2 9(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-induced GLUT4 expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3 Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration in ob/ob mice. It also increases body weight gain and body fat in weanling mice.4 [Matreya, LLC. Catalog No. 1278]
IC 50Human Endogenous Metabolite
References1.Shultz, T.D., Chew, B.P., Seaman, W.R., et al.Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cellsCancer Lett.63(2)125-133(1992) 2.Moya-Camarena, S.Y., Heuvel, J.P.V., Blanchard, S.G., et al.Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARαJ. Lipid Res.40(8)1426-1433(1999) 3.Moloney, F., Toomey, S., Noone, E., et al.Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissueDiabetes56(3)574-582(2007) 4.Pariza, M.W., Park, Y., and Cook, M.E.The biologically active isomers of conjugated linoleic acidProg. Lipid Res.40(4)283-298(2001)
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Preparation Products And Raw materials
Tag:9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)(756499-04-4) Related Product Information
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