- Methyl (R)-(+)-lactate
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- $0.00 / 1KG
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2026-04-03
- CAS:17392-83-5
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 5000kg/month
- Methyl (R)-(+)-lactate
-
- $10.00 / 1KG
-
2026-03-20
- CAS:17392-83-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
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| | Methyl (R)-(+)-lactate Basic information |
| | Methyl (R)-(+)-lactate Chemical Properties |
| alpha | 8.5 º (c=neat) | | Boiling point | 144-145 °C(lit.) | | density | 1.09 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.413(lit.) | | Fp | 121 °F | | storage temp. | Inert atmosphere,2-8°C | | solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly) | | pka | 13.07±0.20(Predicted) | | form | Liquid | | color | Clear colorless | | Optical Rotation | [α]21/D +8.4°, neat | | Water Solubility | miscible, hydrolyses | | Merck | 14,6094 | | InChI | 1S/C4H8O3/c1-3(5)4(6)7-2/h3,5H,1-2H3/t3-/m1/s1 | | InChIKey | LPEKGGXMPWTOCB-GSVOUGTGSA-N | | SMILES | COC(=O)[C@@H](C)O | | LogP | -0.719 (est) | | CAS DataBase Reference | 17392-83-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 10-36/37 | | Safety Statements | 16-24-24/25 | | RIDADR | UN 3272 3/PG 3 | | WGK Germany | 1 | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29181100 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Eye Irrit. 2
Flam. Liq. 3
STOT SE 3 |
| | Methyl (R)-(+)-lactate Usage And Synthesis |
| Chemical Properties | Colorless to light yellow liqui | | Uses | (+)-Methyl D-lactate can be used as a starting material in the asymmetric preparation of:
- Neomethymycin, a macrolide which contains 12-membered macrolactone that is used as a potent biological agent.
- PM-toxin A.
It can also be used as a chiral pool along with D-(-)-tartaric acid in the stereoselective total synthesis of separacenes A and B via Trost-Rychnovsky alkyne rearrangement, Horner-Wadsworth-Emmons olefination as well as Corey-Bakshi-Shibata reaction. | | Definition | ChEBI: A methyl lactate that has R configuration. | | General Description | This compound has benign qualities and is biodegradable, water miscible, and functions as a versatile solvent for CA membrane preparation. This is also used as an intermediate for the production of other chemicals, polymers, and derivatives. Thus this product has been enhanced for Safer solvents and auxiliaries. | | Synthesis | The general procedure for the synthesis of L-lactic acid and D-lactic acid methyl ester from methyl lactate was as follows: in a standard 500-μL hydrolysis reaction system, 140 μg of purified esterase PHE14, 50 mmol/L of racemic methyl lactate as substrate, and 50 mmol/L of phosphate buffer (pH 7.5) were added. The reaction system was incubated at 37°C for 1 hour. Upon completion of the reaction, the reaction samples were extracted using an equal volume of ethyl acetate, and the organic phase was subsequently analyzed to assess the enzymatic disassembly of (±)-lactic acid methyl ester. | | References | [1] Chinese Journal of Catalysis, 2016, vol. 37, # 8, p. 1396 - 1402
[2] Green Chemistry, 2013, vol. 15, # 10, p. 2817 - 2824 |
| | Methyl (R)-(+)-lactate Preparation Products And Raw materials |
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